Application

PTH / arathyroid hormone EIA kit has been used to determine parathyroid hormone (PTH) levels in human embryonic kidney (HEK293) cells.

Biochem/physiol Actions

Parathyroid hormone (PTH) plays a vital role in regulation calcium homeostasis. It increases bone mass in animals and humans by inhibiting osteoblast apoptosis. PTH has potential applications in preventing fractures in postmenopausal women with osteoporosis. Irregular diurnal patterns of PTH leads to sustained mild hypercalcemia in non dialyzed chronic kidney disease (CKD) patients. PTH, along with other heart failure biomarkers play a vital role in measuring disease severity and prognosis of heart failure with preserved ejection fraction (HFpEF). Variation in PTH leads to osteoporosis in asymptomatic hyperparathyroidism (HPT).

General description

The PTH Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting PTH peptide based on the principle of Competitive Enzyme Immunoassay.

Immunogen

Parathyroid Hormone (PTH), synthetic peptide