PHR1404-1G Display Image

Cyclophosphamide

Code: PHR1404-1G D2-231

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

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£101.52 1G

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Cyclophosphamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

Biochem/physiol Actions

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0295 in the slot below. This is an example certificate only and may not be the lot that you receive.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Cyclophosphamide is one of the cytostatic compounds that is a constituent of several polychemotherapy regimens.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

agencytraceable to USP 1157002, traceable to Ph. Eur. C3250000
application(s)pharmaceutical (small molecule)
CofAcurrent certificate can be downloaded
formatneat
gradepharmaceutical secondary standard, certified reference material
InChI keyPWOQRKCAHTVFLB-UHFFFAOYSA-N
InChI1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
mp49-51 °C (lit.)
packagingpkg of 1 g
Quality Level300
SMILES string[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
storage temp.2-8°C
technique(s)gas chromatography (GC): suitable, HPLC: suitable
Cas Number6055-19-2
Hazard Class6.1
Un Number3464
Pack GroupIII
This product has met the following criteria: