EZGLP1T-36K Display Image

GLP-1 Total ELISA Kit

Code: EZGLP1T-36K D2-231

Application

Used to detect/quantify: Glucagon Like Peptide-1

This is a 3.5-hour assay at room temperature requiring 50 uL of serum, plasma or culture samples per well.<...


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Application

Used to detect/quantify: Glucagon Like Peptide-1

This is a 3.5-hour assay at room temperature requiring 50 uL of serum, plasma or culture samples per well.

Research CategoryMetabolism

Disclaimer

For research use only. Not for use in diagnostic procedures.

General description

Glucagon-like peptide-1 (GLP-1) is a 30 amino acid gut hormone secreted from the intestinal L-cells. The GLP-1 sequence is highly conserved among mammals and is released in its active form (7-36) in response to food intake. It is quickly degraded into its inactive form (9-36) after cleavage by DPPIV. GLP-1 reduces glucose levels by regulating pancreatic secretion, slowing gastric emptying and lowering the desire for food intake. Therefore, it is an important biomarker for the study of diabetes and obesity. This kit measures both the active (7-36) and inactive (9-36) forms of GLP-1.

Specificity

Cross ReactivtyGLP-1 is conserved in almost all mammals.

The antibody pair used in this assay is specific to GLP-1 (7-36) and (9-36) and has no cross-reactivity with GLP-2, GIP, Glucagon or Oxyntomodulin.

assay rangerecovery range: 90-110%, linearity: 90-132%, standard curve range: 4.1-1000 pM, inter-assay cv: ﹤12%intra-assay cv: ﹤5%, sensitivity: 1.5 pM(MinDC)
Gene Informationhuman ... GCG(2641)
NCBI accession no.NM_002054.2
Quality Level100
species reactivityhuman, rat, mouse
technique(s)ELISA: suitable
UniProt accession no.P01275
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