C-106-1ML Display Image

Cortisol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

Code: C-106-1ML D2-231

Application

This Certified Reference Material (CRM) in solution can also be used as follows:•Development of a disposable immunosensor based on direct competitive-enzyme ...


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Application

This Certified Reference Material (CRM) in solution can also be used as follows:•Development of a disposable immunosensor based on direct competitive-enzyme linked immunoassay (DC-ELISA) to determine cortisol in human saliva samples•Quantitative analysis of cortisol in human hair samples by a liquid-chromatography-tandem mass spectrometric (LC-MS/MS) method•Selective and sensitive analysis of both cortisol and cortisone in human hair samples by an automated solid phase extraction (SPE) method combined with liquid chromatography (LC) coupled to electrospray ionization-tandem mass spectrometry (ESI-MS3)•Multi-residue determination of cortisol, cortisone, and their three tetrahydro metabolites from human urine samples by an LC-MS/MS method•Human saliva analysis for the estimation of cortisol and cortisone by ionic liquid dispersive liquid-liquid microextraction (IL-DLLME) and liquid chromatography combined with ultra-violet/visible (UV/Vis) detection

Features and Benefits

Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability Rigorously tested through real-time stability studies to ensure accuracy and shelf life Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty Flame sealed under argon into ampoules for long-term shelf life Offered in a convenient, DEA-exempt format to improve laboratory efficiency

General description

Cortisol or hydrocortisone, also known as the stress hormone, is aglucocorticoid steroid. It is released by the adrenal glands and is involved inmaintaining the circadian rhythm. The hormone is measured in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing's syndrome, Addison's disease, and Sheehan's syndrome.

Legal Information

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

CERILLIANT is a registered trademark of Cerilliant Corporation

application(s)clinical testingclinical testing
concentration1.0 mg/mL in methanol
featureSnap-N-Spike®/Snap-N-Shoot®
formliquid
formatsingle component solution
Gene Informationhuman ... NR3C1(2908)
gradecertified reference material
InChI keyJYGXADMDTFJGBT-VWUMJDOOSA-N
InChI1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
manufacturer/tradenameCerilliant®
packagingampule of 1 mL
Quality Level300
SMILES stringC[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23
storage temp.−20°C
technique(s)gas chromatography (GC): suitable, liquid chromatography (LC): suitable
Cas Number50-23-7
Hazard Class3
Un Number1230
Pack GroupII
This product has met the following criteria: