41661-250ML Display Image

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, absolute, over molecular sieve (H2O <=0.03%), >=99.0% (GC)

Code: 41661-250ML D2-231

Application

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) can be used as a:Solvent in the synthesis of 1-aryl-3,4,5-substituted pyrazoles by cyclocondens...


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£128.00 250ML
£153.60 inc. VAT
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Application

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) can be used as a:Solvent in the synthesis of 1-aryl-3,4,5-substituted pyrazoles by cyclocondensation of 1,3-diketones with arylhydrazine hydrochlorides.Chelating solvent in the trifluoromethylation of activated and non-activated halogenated double bonds.Ligand in ortho-alkylation of secondary benzamide catalyzed by cobalt.

Other Notes

Aprotic, dipolar solvent, which is an excellent replacement of the carcinogenic HMPA as cosolvent for highly reactive nucleophiles and bases. High Z-selectivity in enolate formation; DMPU was shown to be non-mutagenic and safe.

Packaging

250 mL in Sure/Seal™

1 L in Sure/Seal™

assay≥99.0% (GC)
bp146 °C/44 mmHg (lit.)
density1.06 g/mL at 25 °C (lit.)
formliquid
gradeabsolute
InChI keyGUVUOGQBMYCBQP-UHFFFAOYSA-N
InChI1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3
Quality Level200
qualityover molecular sieve (H2O ≤0.05%)
refractive indexn20/D 1.488 (lit.), n20/D 1.489
SMILES stringCN1CCCN(C)C1=O
Code
Description
Unit Size
List Price
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41661-1L
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, absolute, over molecular sieve (H2O <=0.03%), >=99.0% (GC)

Unit:1L
List Price: £435.00
Source:List Price
ADD
Cas Number7226-23-5
This product has met the following criteria: