A4660-2.5MG Display Image

6-Thioguanine, Hybri-Max, 50 x, gamma-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

Code: A4660-2.5MG D2-231

Application

Used in hybridoma formation applications as a selection agent.

Biochem/physiol Actions

Ribosylated and phosphorylated by the same pat...


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£27.50 2.5MG
£33.00 inc. VAT
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Application

Used in hybridoma formation applications as a selection agent.

Biochem/physiol Actions

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Reconstitution

Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 µM 2-amino-6-mercaptopurine.

assay~98%
biological sourcesynthetic (organic)
concentration50 ×
formlyophilized powder
Gene Informationhuman ... IMPDH1(3614), IMPDH2(3615)
gradeHybri-Max™
impuritiesendotoxin, tested
InChI keyWYWHKKSPHMUBEB-UHFFFAOYSA-N
InChI1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
mp≥300 °C (lit.)
product lineBioXtra
Quality Level200
SMILES stringNC1=Nc2nc[nH]c2C(=S)N1
solubility1 M NaOH: 50 mg/mL, clear to slightly hazy
sterilityγ-irradiated
storage temp.room temp
technique(s)cell culture | hybridoma: suitable
Cas Number154-42-7
Hazard Class6.1
Un Number2811
Pack GroupIII
Pack2.5MG
This product has met the following criteria: