Application
Reactant for:• Preparation of hexapeptide key fragments via stereoselective selenocyclization/oxidative deselenylation or hydrazination/cyclization reactions• Asymmetric Michael addition reactions• Preparation of dipeptidyl peptidase IV dependent water-soluble prodrugs via Mitsunobu reaction• Synthesis of pyrroloisoquinoline template via stereoselective N-acyliminium-mediated cyclization and enolate amination for synthesis of peptidomimetic compounds• Barbier-type propargylation reactions• Synthesis of bacterial peptide deformylase (PDF) inhibitor fumimycin• Asymmetric amination of glycine Schiff bases
General description
Di-tert-butyl azodicarboxylate is a an acid labile reagent for Mitsunobu reactions allowing facile isolation of products and for the electrophilic amination and hydrazination of enolates and lithium alkyls.
This product has met the following criteria: