D9891-25G Display Image

Doxycycline hyclate, >=98% (TLC)

Code: D9891-25G D2-231

Application

Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoi...


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£470.00 25G
£564.00 inc. VAT

Application

Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.

Doxycycline hyclate has been used for the induction of glioma cells and human embryonic kidney 293T cells (HEK293T).

Biochem/physiol Actions

Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.

General description

Doxycycline hyclate belongs to the second generation of tetracycline antibiotics family. Doxycycline hyclate shows minimal side effects upon usage. It is effective for the treatment of recurrent aphthous stomatitis (RAS) and promotes speedy recovery.

Chemical structure: tetracycline

Packaging

1, 5, 10, 25, 100 g in glass bottle

antibiotic activity spectrummycoplasma, parasites, Gram-positive bacteria, Gram-negative bacteria
assay≥93.5% (HPLC), 95.0-102.0% anhydrous basis (ethanol free based)
biological sourcesynthetic
coloryellow to yellow-green
formpowder
InChI keyHALQELOKLVRWRI-ZVACAFRPSA-N
InChI1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1
mode of actionprotein synthesis | interferes
mp~201 °C
Quality Level200
SMILES stringCl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58
solubilitywater: soluble 50 mg/mL, clear, yellow-green
storage temp.2-8°C
Code
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Unit Size
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D9891-1G
Unit:1G
List Price: £53.10
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D9891-100G
Unit:100G
List Price: £1,130.00
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D9891-5G
Unit:5G
List Price: £137.00
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D9891-10G
Unit:10G
List Price: £235.00
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Cas Number24390-14-5
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