94646-1KG-F Display Image

Poly(ethylene glycol), BioUltra, 35,000

Code: 94646-1KG-F D2-231

Application

Poly(ethylene glycol) has been used: as a component of University of Wisconsin (UW) cold preservation solutions to stabilize the cell membrane of hepatocytes duri...


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£114.00 1KG

Application

Poly(ethylene glycol) has been used: as a component of University of Wisconsin (UW) cold preservation solutions to stabilize the cell membrane of hepatocytes during temperature changesas a component of the supercooling solution to study supercooling preservation technique of the rat liver for transplantation and to protect against hypothermic injuryto prepare aqueous phase for the fabrication of multicellular spheroid (MCS) cultures

Biochem/physiol Actions

Polyethylene glycol (PEG) is a synthetic polymer that is used as a gold standard in bioconjugation and nanomedicine to extend blood circulation time and enhance drug efficacy. It acts as an ice-modulator by preventing ice crystallization, which is beneficial for cellular membranes. PEG provides protection against hypothermic injury, like lipid peroxidation and cell membrane injury. PEG-conjugated drugs are considered safe for use in humans and are approved by the U.S. Food and Drug Administration (FDA). PEG has several biomedical applications, including biosensing, imaging, and tissue engineering. It also repels protein adsorption and lowers the liver uptake, which helps in coating nanoparticles.

General description

Polyethylene glycol (PEG) is a polyether compound that is used as an additive in cosmetics, pharmaceuticals, and food. It consists of repeated ethylene glycol units[-(CH2CH2O)n].

λ50 mg/mL in H2O
anion tracessulfate (SO42-): ≤50 mg/kg, chloride (Cl-): ≤50 mg/kg
cation tracesBi: ≤5 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Li: ≤5 mg/kg, K: ≤200 mg/kg, Na: ≤200 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formpowder or crystals (or flakes)
impurities≤0.005% peroxides (as H2O2):, insoluble matter:, passes filter test
InChI keyLYCAIKOWRPUZTN-UHFFFAOYSA-N
InChI1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
mol wtMr ~35000
mp64-66 °C
pH5.5-7.0 (25 °C, 50 mg/mL in H2O)
product lineBioUltra
Quality Level200
SMILES stringC(CO)O
solubilityH2O: 50 mg/mL at 25 °C, clear, colorless
UV absorptionλ: 280 nm Amax: 0.12, λ: 260 nm Amax: 0.12
Code
Description
Unit Size
List Price
Qty
94646-250G-F
Unit:250G
List Price: £35.90
Source:List Price
ADD
Cas Number25322-68-3
This product has met the following criteria: