87128-100G Display Image

Tetracycline, >=98.0% (NT)

Code: 87128-100G D2-231

Biochem/physiol Actions

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis b...


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Your Price
£144.00 100G
£172.80 inc. VAT

Biochem/physiol Actions

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.

General description

Chemical structure: tetracycline

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Hygroscopic. Light sensitive. Keep in a dry place.

Packaging

25g, 100g

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
assay98.0-102.0% (HPLC)
biological sourcesynthetic
colorfaint yellow to dark yellow
formpowder or crystals
Gene Informationhuman ... CYP1A2(1544), TERT(7015)
InChI keyOFVLGDICTFRJMM-WESIUVDSSA-N
InChI1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
mode of actionprotein synthesis | interferes
mp172-174 °C (dec.)
Quality Level200
SMILES stringCN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
87128-25G
Unit:25G
List Price: £42.90
Source:List Price
ADD
Cas Number60-54-8
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