S4451-5MG Display Image

Sal003, >=98% (HPLC)

Code: S4451-5MG D2-231

Application

Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.

Biochem/physiol Actions

Sal003 inh...


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Application

Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.

Biochem/physiol Actions

Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4.

Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
compatibilityfor use with Bio-Rad CFX96
formpowder
InChI keyTVNBASWNLOIQML-IZZDOVSWSA-N
InChI1S/C18H15Cl4N3OS/c19-13-7-9-14(10-8-13)23-17(27)25-16(18(20,21)22)24-15(26)11-6-12-4-2-1-3-5-12/h1-11,16H,(H,24,26)(H2,23,25,27)/b11-6+
Quality Level100
SMILES stringClc1ccc(NC(=S)NC(NC(=O)C=Cc2ccccc2)C(Cl)(Cl)Cl)cc1
solubilityDMSO: ≥10 mg/mL
storage conditiondesiccated, protect from light
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
S4451-25MG
Sal003, >=98% (HPLC)

Unit:25MG
List Price: £580.00
Source:List Price
ADD
Cas Number1164470-53-4
This product has met the following criteria: