S3445-5MG Display Image

SM-19712 hydrate, >=98% (HPLC)

Code: S3445-5MG D2-231

Application

SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimer′s disease.

Biochem/physiol...


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Application

SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimer′s disease.

Biochem/physiol Actions

SM-19712 a sulfonylureid-pyrazole derivative is a potent and selective inhibitor of endothelin converting enzyme (ECE). It attenuates the effects of ischemic acute renal failure and reduces the inflammation, tissue injury and vasoconstriction induced by dextran sodium sulfate in mouse colon.

Nonpeptide, potent and selective endothelin converting enzyme inhibitor.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloroff-white to light brown
formpowder
InChI keyHLHPDQXMLDUDQV-UHFFFAOYSA-M
InChI1S/C12H10ClN5O3S.Na.H2O/c1-7-10(6-14)11(17-16-7)15-12(19)18-22(20,21)9-4-2-8(13)3-5-9;;/h2-5H,1H3,(H3,15,16,17,18,19);;1H2/q;+1;/p-1
Quality Level100
SMILES stringClC1=CC=C(S(N(C(NC2=C(C#N)C(C)=NN2C3=CC=CC=C3)=O)[Na])(=O)=O)C=C1
solubilityDMSO: ≥20 mg/mL, H2O: ≥20 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
S3445-25MG
SM-19712 hydrate, >=98% (HPLC)

Unit:25MG
List Price: £546.00
Source:List Price
ADD
Cas Number194542-56-8
This product has met the following criteria: