N7261-10G Display Image

Nortriptyline hydrochloride, >=98% (TLC), powder

Code: N7261-10G D2-231

Biochem/physiol Actions

Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (K<...


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Biochem/physiol Actions

Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (Ki = 161 nM). 5-HT2 serotonin receptor antagonist.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

assay≥98% (HPLC)
colorwhite to off-white
formpowder
Gene Informationhuman ... HTR2A(3356), HTR2B(3357), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)
InChI keySHAYBENGXDALFF-UHFFFAOYSA-N
InChI1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
originatorEli Lilly
Quality Level200
SMILES stringCl.CNCCC=C1c2ccccc2CCc3ccccc13
solubilityH2O: soluble, ethanol: 100 mg/mL
Cas Number894-71-3
This product has met the following criteria: