G8877-10MG Display Image

Guanosine 5-triphosphate sodium salt hydrate, >=95% (HPLC), powder

Code: G8877-10MG D2-231

Application

Guanosine 5′-triphosphate sodium salt hydrate has been used:in the preparation of horseradish peroxidase (HRP)-modified platination reagentsin whole cell, voltage...


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Your Price
£23.40 10MG

Application

Guanosine 5′-triphosphate sodium salt hydrate has been used:in the preparation of horseradish peroxidase (HRP)-modified platination reagentsin whole cell, voltage-clamp recordingsin in vitroinhibition of transglutaminase (tTG)

Biochem/physiol Actions

GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1 g in poly bottle

10, 25, 100, 250 mg in poly bottle

Preparation Note

Prepared by enzymatic phosphorylation of 5′-GMP.

assay≥95% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... HRAS(3265)
InChI keyKZRMTEVIDYXWQW-CYCLDIHTSA-K
InChI1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
Quality Level200
shipped indry ice
SMILES string[Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1
solubilityH2O: 50 mg/mL
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
G8877-100MG
Unit:100MG
List Price: £128.00
Source:List Price
ADD
G8877-250MG
Unit:250MG
List Price: £201.00
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G8877-1G
Unit:1G
List Price: £635.00
Source:List Price
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G8877-25MG
Unit:25MG
List Price: £41.10
Source:List Price
ADD
Cas Number36051-31-7
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