8-Cyclopentyl-1,3-dipropylxanthine, solid

Code: C101-25MG D2-231

Application

8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It...


read more

Your Price
£86.20 25MG
£103.44 inc. VAT
REQUEST

Application

8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It has also been used as A1AR antagonist in MCF-7 breast cancer cell line to test its anti-cancer effect.

Biochem/physiol Actions

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective A1adenosine receptor antagonist. DPCPX possesses anti-cancer functionality. It induces apoptosis in breast cancer cells and favors mRNA expression of caspases.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

25, 100 mg in poly bottle

εmax14,800 at 276 nm in ethanol
colorwhite
formsolid
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora2b(29316), Adora3(25370)
InChI keyFFBDFADSZUINTG-UHFFFAOYSA-N
InChI1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
Quality Level100
SMILES stringCCCN1C(=O)N(CCC)c2nc([nH]c2C1=O)C3CCCC3
solubilityethanol: 4 mg/mL, DMSO: >10 mg/mL, H2O: insoluble, 0.1 M NaOH: 2 mg/mL
Code
Description
Unit Size
List Price
Qty
C101-100MG
8-Cyclopentyl-1,3-dipropylxanthine, solid

Unit:100MG
List Price: £258.00
Source:List Price
ADD
Cas Number102146-07-6
This product has met the following criteria: