SAB1404245-100UG Display Image

Monoclonal Anti-PRKDC, (C-terminal) antibody produced in mouse, clone 2A8, purified immunoglobulin, buffered aqueous solution

Code: SAB1404245-100UG D2-231

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to b...


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Your Price
£415.00 100UG
Discontinued
£498.00 inc. VAT

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM

Immunogen

PRKDC (NP_008835, 4019 a.a. ~ 4128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGREPWM

Physical form

Solution in phosphate buffered saline, pH 7.4

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
clone2A8, monoclonal
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... PRKDC(5591)
isotypeIgG2aκ
mol wtantigen ~38.21 kDa
NCBI accession no.NM_006904
Quality Level100
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)indirect ELISA: suitable, capture ELISA: suitable, western blot: 1-5 µg/mL, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunofluorescence: suitable
UniProt accession no.P78527
This product has met the following criteria: