Anti-ACSS1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution

Biochem/physiol Actions

The enzyme coded by ACSS1 gene is responsible for the conversion for acetate to acetyl CoA in the mitochondria. It thereby contributes to energy production during ketosis, especially in the heart and skeletal muscle.

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General description

ACSS1 (acyl-CoA synthetase short chain family member 1) gene is mapped to human chromosome 20p11.21. The protein is highly expressed in heart and skeletal muscles.

Immunogen

ACSS1 (AAH39261.1, 1 a.a. ~ 689 a.a) full-length human protein.SequenceMAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVMEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLRKIITSEAQELGDTTTLEDPSIIAEILSVYQKCKDKQAAAK

Physical form

Solution in phosphate buffered saline, pH 7.4