Anti-Nicastrin (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Application

Anti-Nicastrin has been used in western blotting.

Biochem/physiol Actions

Nicastrin (NCSTN) helps in the assembly of γ-secretase complex. It is associated with Alzheimer′s disease.

Disclaimer

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General description

Nicastrin (NCSTN) is a transmembrane glycoprotein, that is located on chromosome 1q23.

Immunogen

a 18 amino acid peptide from near the center of human Nicastrin.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3985.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide