Biochem/physiol Actions

Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRα is selectively expressed in kidney, heart, cerebellum, intestine and skeletal muscle. It is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic peptide M(1)SSQVVGIEPL­YIKAE(16) corresponding to amino acid residues 1-16 from human ERR1 protein.

Physical form

Provided as ~100 µg of affinity purified antibody (1 mg/mL) in phosphate buffered saline containing 1 mg/mL bovine serum albumin and 0.05% sodium azide.