Analysis Note

Positive ControlAlzheimer's disease brain tissue

Application

ELISA (≥1:250,000)Paraffin Sections (≥1:200, proteinase K pre-treatment recommended; see figure legend, see application references)

General description

This Anti-8-Hydroxyguanosine Goat polyclonal antibody detects 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue. It is validated for use in ELISA and with paraffin sections.

Goat polyclonal antibody supplied as undiluted serum. Recognizes 8-hydroxydeoxy-guanosine.

Recognizes 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue.

Immunogen

8-Hydroxyguanosine

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Does not cross-react with other naturally occurring nucleotides. Antibody should be titrated for optimal results in individual systems.

Abe, T., et al. 2003. Neurosci. Lett.336, 105.Parker, A.R., et al. 2002. Cancer Res.62, 7230.

Packaging

100 µL in Plastic ampoule

Physical form

Undiluted serum.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)