P8624-10MG Display Image

Pirarubicin, >=95% (HPLC)

Code: P8624-10MG D2-231

Application

Pirarubicin is used to study synergistic cytotoxicity and apoptosis of cancer cells. It is used to study how to protect multi-drug resistance cells from anthracyc...


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£379.00 10MG
£454.80 inc. VAT
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Application

Pirarubicin is used to study synergistic cytotoxicity and apoptosis of cancer cells. It is used to study how to protect multi-drug resistance cells from anthracycline induced cytotoxicity.

Biochem/physiol Actions

Pirarubicin, an anthracycline antibiotic that is an analog of doxorubicin, is an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter.1,2 It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

10mg,25mg

antibiotic activity spectrumneoplastics
assay≥95% (HPLC)
formpowder
InChI keyKMSKQZKKOZQFFG-NCXNULAVSA-N
InChI1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21?,22-,31+,32-/m0/s1
mode of actionDNA synthesis | interferes, enzyme | inhibits
Quality Level200
shipped inwet ice
SMILES stringCOc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](OC6CCCCO6)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
solubilityethanol: soluble 25 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
P8624-25MG
Pirarubicin, >=95% (HPLC)

Unit:25MG
List Price: £756.00
Source:List Price
ADD
Cas Number72496-41-4
This product has met the following criteria: