30450-5MG Display Image

Daunorubicin hydrochloride, >=90% (HPLC)

Code: 30450-5MG D2-231

Application

Daunorubicin hydrochloride is used in photostability, antileukemic, and drug metabolism studies.

Biochem/physiol Actions

Potent antic...


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Your Price
£120.00 5MG
£144.00 inc. VAT

Application

Daunorubicin hydrochloride is used in photostability, antileukemic, and drug metabolism studies.

Biochem/physiol Actions

Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.

On binding to DNA, daunomycin intercalates, with its daunosamine residue directed toward the minor groove. Daunomycin effectively binds to every 3 base pairs which causes unwinding.

General description

Chemical structure: aminoglycoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas.

Packaging

5 mg, 25 mg

antibiotic activity spectrumneoplastics
assay≥90% (HPLC)
biological sourcesynthetic
colorred to deep red
formpowder
Gene Informationhuman ... TOP2A(7153)
InChI keyGUGHGUXZJWAIAS-QQYBVWGSSA-N
InChI1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
mode of actionDNA synthesis | interferes
Quality Level200
SMILES stringCl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
30450-25MG
Unit:25MG
List Price: £478.00
Source:List Price
ADD
Cas Number23541-50-6
Hazard Class6.1
Un Number2811
Pack GroupIII
This product has met the following criteria: