Biochem/physiol Actions

TC3.6 is a PDE7 selective inhibitor (IC₅₀ = 1.04 µM). In an Experimental Autoimmune Encephalomyelitis (EAE) murine model, TC3.6 reduced levels of IL-17, blocked infiltration of immune cells into the CNS and elevated levels of the Treg marker Foxp3. TC3.6 also enhances survival and differentiation of oligodendrocyte precursor cells.

Features and Benefits

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Packaging

5, 25 mg in glass bottle