Application

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess in vitro hemostatic properties of French lyophilized plasma.

General description

Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.

Packaging

150 units in glass bottle

Physical form

supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride

Unit Definition

Activity is expressed in NIH units obtained by direct comparison to a NIH thrombin reference standard.