SML1605-25MG Display Image

OTX015

Code: SML1605-25MG D2-231

Biochem/physiol Actions

OTX015 is a potent inhibitor of the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4).

It binds to bromodomain and extra-terminal domain (BET) pro...


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£971.00 25MG
£1,165.20 inc. VAT
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Biochem/physiol Actions

OTX015 is a potent inhibitor of the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4).

It binds to bromodomain and extra-terminal domain (BET) proteins and inhibits their binding to the chromatin. This in turn prevents gene transcription. OTX015 has been shown to inhibit proliferation of cells in haematological malignancies.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to light brown
formpowder
Gene Informationhuman ... BRD2(6046), BRD3(8019), BRD4(23476), BRDT(676)
InChI keyGNMUEVRJHCWKTO-FQEVSTJZSA-N
InChI1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33)/t20-/m0/s1
Quality Level100
SMILES stringO=C(NC(C=C1)=CC=C1O)C[C@H]2C3=NN=C(C)N3C(SC(C)=C4C)=C4C(C5=CC=C(Cl)C=C5)=N2
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
Code
Description
Unit Size
List Price
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SML1605-5MG
OTX015

Unit:5MG
List Price: £251.00
Source:List Price
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Cas Number202590-98-5
This product has met the following criteria: