Panepoxydone is a fungal metabolite that inhibits NF-?B transcription factor by preventing I?B phosphorylation, thus inhibiting the release of NF-?B from the I?B : NF-?B complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi.
Store the product sealed at -20 °C, protect from light. Under these conditions, the product is stable for at least 2 years.
Soluble in ethyl acetate, ethanol, and DMSO (10mg/ml). The product is soluble, but not stable in water and methanol.