Alantolactone, >=98% (HPLC)

Code: SML0415-5MG D2-231

Application

Alantolactone has been used:in cell viability assayto examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)...


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£97.50 5MG
£117.00 inc. VAT
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Application

Alantolactone has been used:in cell viability assayto examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)in assessment of degranulation

Biochem/physiol Actions

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

General description

Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyPXOYOCNNSUAQNS-AGNJHWRGSA-N
InChI1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
Quality Level100
SMILES stringC[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12
solubilityDMSO: 15 mg/mL (clear solution)
storage conditiondesiccated, protect from light
storage temp.−20°C
Cas Number546-43-0
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