SML0022-5MG Display Image

IMB-10, >=98% (HPLC)

Code: SML0022-5MG D2-231

Application

IMB-10 may be used to study integrin-mediated signaling in tumor cells.

Biochem/physiol Actions

IMB-10 is a thioxothiazolidine compou...

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£141.77 5MG
List Price

Application

IMB-10 may be used to study integrin-mediated signaling in tumor cells.

Biochem/physiol Actions

IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression.

IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.

Packaging

5, 25 mg in glass bottle

solubilityDMSO: ≥25 mg/mL
SMILES stringCc1ccccc1N2C(=S)SC(=CC=Cc3ccccc3)C2=O
assay≥98% (HPLC)
Quality Level100
storage temp.2-8°C
formpowder
coloryellow
InChI keyUYZLENPCNZVWQZ-QHMSGILQSA-N
InChI1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+

Code
Description
Unit Size
List Price
Qty
SML0022-25MG
Unit:25MG
List Price: £487.28
Source:List Price
ADD
Cas Number307525-40-2