alpha-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, >=90% (SDS-PAGE), lyophilized powder

Code: S4447-500UG D2-231

Biochem/physiol Actions

Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mut...


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£539.00 500UG
Discontinued
£646.80 inc. VAT

Biochem/physiol Actions

Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A tran­sition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein.

Deposition of α-synuclein as fibrillary tangles is a hallmark of certain neurodegenerative diseases including Parkinson′s. Among the familial mutations of α-synuclein, E46K has the greatest potential to aggregate.

assay≥90% (SDS-PAGE)
compatibilityfor use with ABI StepOnePlus
formlyophilized powder
Gene Informationhuman ... SNCA(6622)
mol wtapparent mol wt 19-20 kDa
Quality Level200
recombinantexpressed in E. coli
shipped indry ice
storage temp.−20°C
UniProt accession no.P37840
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