Rubitecan,

Code: R3655-10MG D2-231

Biochem/physiol Actions

Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of ...


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£49.50 10MG
£59.40 inc. VAT
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Biochem/physiol Actions

Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer.

Packaging

50 mg in poly bottle

10 mg in glass insert

assay≥98% (HPLC)
biological sourcesynthetic (organic)
formpowder
InChI keyVHXNKPBCCMUMSW-FQEVSTJZSA-N
InChI1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1
mp182-186 °C
Quality Level100
SMILES stringCC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(cccc5nc34)[N+]([O-])=O)C2=O
solubilityDMSO: 1 mg/mL
storage temp.room temp
Cas Number91421-42-0
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