Application
Pipamperone dihydrochloride may be used: as an internal standard in liquid chromatography with coulometric detectionas an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channelas an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis
Biochem/physiol Actions
Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist; antipsychotic.
Features and Benefits
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Packaging
100 mg in poly bottle
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