Application

Lidocaine may be used for drug testing and for voltage clamp experiments.

Biochem/physiol Actions

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Lidocaine, a neuroprotective agent, mediates blockage of sodium (Na⁺) channels. It prevents the influx of sodium ions leading to depolarization of sodium channels and metabolically inactivated in liver. Lidocaine has positive effect on cerebral ischemia. It is also used in the treatment ofventricular tachycardia. Lidocaine is an efficient anesthetic agent in ophthalmic surgeries as it is highly potent and has good tissue penetrability.

General description

Lidocaine is a local anesthetic and an effective antiarrhythmiaagent. It occurs as solutions of crystalline colorless solid for injections, that has a short half-life within plasma.

Packaging

25, 100 g in poly bottle