Application

Lectin from Triticum vulgaris (wheat) has been used:to conjugate with N-hydroxysuccinimide (NHS) dyeto inhibit nuclear importto inhibit the nuclear pore of human cervical carcinoma HeLa and SiHa cells

Biochem/physiol Actions

WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.

Lectin from Triticum vulgaris (wheat) possessing four binding sites is specific for N-acetyl-d-glucosamine and N-acetyl-d-neuraminic acid (sialic acid) residues. Lectins also function as a fungicide. They also possess anti-nutritive effects.

General description

Lectin from Triticum vulgaris (wheat) is a dimeric glycoprotein of 36 kDa. It belongs to the family of chitin-binding proteins. Glycosylated precursor of lectin is synthesized in endoplasmic reticulum.

Other Notes

Highly purified

Preparation Note

Conjugates are prepared from affinity purified lectin.