A5376-500G Display Image

Acetylsalicylic acid, >=99.0%, crystalline

Code: A5376-500G 505

Acetylsalicylic acid blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is...

read more

ADD
£31.60 EACH List Price
Only available to UK customers

Acetylsalicylic acid blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

  • Synonym: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
  • CAS Number: 50-78-2
  • Linear Formula: 2-(CH3CO2)C6H4CO2H
  • Molecular Weight: 180.16
  • Beilstein Registry Number: 779271
  • EC Number: 200-064-1
  • MDL Number: MFCD00002430
  • PubChem Substance ID: 24278218
  • InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
  • Assay: ≥99.0%
  • Form: Powder
  • Colour: White
  • pKa (25 °C): 3.5
  • mp: 134-136 °C (lit.)
  • Solubility: H2O: 10 mg/mL at 37 °C(lit.), H2O: 3 mg/mL at 25 °C(lit.), Ethanol: 50 mg/mL, Aqueous base: decomposes
  • Absorption: ε1mM/230 nm, aqueous acid 466, ε1mM/231 nm, aqueous base 409, ε1mM/278 nm, aqueous acid 68, ε1mM/298 nm, aqueous base 190
  • Gene Information: Human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)
Synonym
2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
CAS Number
50-78-2
Linear Formula
2-(CH3CO2)C6H4CO2H
Molecular Weight
180.16
Beilstein Registry Number
779271
EC Number
200-064-1
MDL Number
MFCD00002430
PubChem Substance ID
24278218
InChI Key
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Assay
≥99.0%
Form
Powder
Colour
White
pKa (25 °C)
3.5
mp
134-136 °C (lit.)
Solubility
H2O: 10 mg/mL at 37 °C(lit.)
H2O: 3 mg/mL at 25 °C(lit.)
Ethanol: 50 mg/mL
Aqueous base: decomposes
Absorption
ε1mM/230 nm, aqueous acid 466
ε1mM/231 nm, aqueous base 409
ε1mM/278 nm, aqueous acid 68
ε1mM/298 nm, aqueous base 190
Gene Information
Human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)
Code
Description
Unit Size
List Price
Qty