Application
DL-2-Amino-5-phosphonopentanoic acid has been used:• in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses• used in growth medium for inhibition of electrical activity in the neuronal network• used to isolate N-methyl-D-aspartate receptors (NMDAR) or a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product• used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)
Biochem/physiol Actions
Anticonvulsant; potent and selective NMDA receptor antagonist.
Caution
Hygroscopic
Features and Benefits
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Legal Information
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Packaging
10, 25, 50, 100 mg in glass bottle