Biochem/physiol Actions
PI(3,4)P2 plays a role in protein kinase B (PKB) phosphorylation on Ser473 in mast cells. It also binds to certain effectors such as serine/threonine-specific protein kinase (AKT) and dual adaptor of phosphotyrosine and 3-phosphoinositides 1 (DAPP1). It also regulates the activity of actin mesh which is associated with endocytic structures.
General description
PI(3,4)P2 is a lipid secondary messenger. It is obtained from the dephosphorylation of PI(3,4,5)P3 by 5-phosphatase.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-100UG) 2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-500UG)
This product has met the following criteria: