FITC-CM-Dextran, average mol wt 150,000

Code: 74817-1G D2-231

Application

FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative ...


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£219.00 1G
£262.80 inc. VAT

Application

FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative charge. It is also a suitable molecule to be used in encapsulation studies for polymersomal drug delivery systems or Ps DDS . FITC-CM-Dextran is a biocompatible molecule used as a starting material in several pharmaceutical and diagnostic applications.

General description

FITC-CM-Dextran, also known as Fluorescein isothiocyanate–Carboxymethyl–Dextran, is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. FITC-CM-Dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform. FITC-CM-Dextran is manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali, whereby O-carboxymethyl groups are introduced along the dextran chain.

biological sourcesynthetic
compositioncarboxymethyl content, 3-7%
conjugateFITC conjugate
extent of labeling0.001-0.020 mol FITCmol glucose
fluorescenceλex 493 nm; λem 517 nm±5 nm in 0.1 M Tris pH 8.0
formpowder or crystals
mol wtaverage mol wt 150,000
Quality Level100
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