Application
Hippuric acid may be used as an analytical reference standard for the quantification of the analyte in the following:Human biological fluids using high-performance liquid chromatography (HPLC) with UV detection.Human and rat urine samples using gas chromatography–mass spectrometry (GC–MS).Human urine samples using GC equipped with a flame ionization detector.
General description
Hippuric acid, the glycine conjugate of benzoic acid, is formed via a biotransformation process. From scientific literature, it is reported to be found as an excretory product in urine. Hippuric acid is also known to be catabolically synthesized from benzene-type aromatic compounds, believed to be originated from various factors such as environmental exposures, basic human liver metabolism of protein catabolism, cyclic sugar type-compounds, quinic acid, etc.
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