Biochem/physiol Actions
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary TargetPP1, PP2
Target IC50: 10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively
General description
Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.Kiguchi, K., et al. 1994. Cell Growth Differ.5, 995.Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.Kreienbuhl, P., et al. 1992. Blood80, 2911.Nomura, M., et al. 1992. Biochemistry31, 11915.Song, Q., et al. 1992. J. Cell Physiol.153, 550.Tada, Y., et al. 1992. Immunopharmacol.24, 17.
Packaging
50 µg in Alu drum
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Warning
Toxicity: Toxic (F)
This product has met the following criteria: