Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetPP1, PP2

Target IC₅₀: 10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively

General description

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Gjertsen, B.T., et al. 1994. J. Cell Sci.107, 3363.Kiguchi, K., et al. 1994. Cell Growth Differ.5, 995.Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun.197, 916.Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun.189, 950.Kreienbuhl, P., et al. 1992. Blood80, 2911.Nomura, M., et al. 1992. Biochemistry31, 11915.Song, Q., et al. 1992. J. Cell Physiol.153, 550.Tada, Y., et al. 1992. Immunopharmacol.24, 17.

Packaging

50 µg in Alu drum

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Warning

Toxicity: Toxic (F)