43420-5G Display Image
43420-5G Display Image

beta-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate, >=97.0% (HPLC)

Code: 43420-5G D2-231

Application

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrat...

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£634.00 5G
List Price

Application

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Nicotinamide adenine dinucleotide (NAD) and NADH form a redox pair. NAD/NADH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications. NAD is also involved in post-translational (Poly(ADP-ribose) polymerization) modifications of proteins.

Biochem/physiol Actions

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, ß-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Packaging

Packaged by solid weight.

Quality Level200
SMILES stringO.[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
cation tracesK: 200 mg/kg
cation tracesMg: 200 mg/kg
cation tracesCr: 5 mg/kg
cation tracesMn: 5 mg/kg
cation tracesPb: 5 mg/kg
cation tracesFe: 5 mg/kg
cation tracesCa: 200 mg/kg
cation tracesCu: 20 mg/kg
cation tracesZn: 5 mg/kg
cation tracesNi: 5 mg/kg
cation tracesCd: 5 mg/kg
cation tracesCo: 5 mg/kg
InChI1S/C21H29N7O14P2.2Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;;1H2/q;2*+1;/p-2/t10-,11-,13-,14-,15-,16-,20-,21-;;;/m1.../s1
InChI keyFWBNCIFELNNJCX-UHOVGGJYSA-L
storage temp.20C
absorbance ratioA260/340 nm 2.40
assay97.0% (HPLC)

Code
Description
Unit Size
List Price
Qty
43420-100MG
Unit:100MG
List Price: £32.20
Source:List Price
ADD
43420-1G
Unit:1G
List Price: £145.00
Source:List Price
ADD
Cas Number606-68-8