361593-100MG Display Image

Artemisinin, 98%

Code: 361593-100MG D2-231

Application

Artemisinin has been used:in drug susceptibility assaysas a standard for its quantification from artemisinin from hairy rootsto check cell viability using 3-(4, 5...


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£100.00 100MG
£120.00 inc. VAT
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Application

Artemisinin has been used:in drug susceptibility assaysas a standard for its quantification from artemisinin from hairy rootsto check cell viability using 3-(4, 5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) assayas an antimalarial agent to investigate the role of autophagy-related (ATG) genes throughout the P. falciparum asexual and sexual blood stages

Biochem/physiol Actions

Artemisinin (Qinghaosu), a sesquiterpene lactone, is a highly active anti-malarial (falciparum malaria) drug. Artemisinin is also an anthelmintic (parasitic worm) effective against the blood fluke, schistosomiasis.

General description

Artemisinin is extracted from sweet wormwood (Artemisia annua). It has anticancer, antiprotozoal and antiviral activities. Artemisinin is associated with brainstem encephalopathy.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 361593.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

100 mg in glass bottle

antibiotic activity spectrumviruses, parasites
assay98%
formsolid
InChI keyBLUAFEHZUWYNDE-NNWCWBAJSA-N
InChI1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
mode of actionenzyme | inhibits
mp156-157 °C (lit.)
optical activity[α]20/D +76°, c = 0.5 in methanol
Quality Level100
SMILES stringC[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4
Cas Number63968-64-9
This product has met the following criteria: