Biochem/physiol Actions
Primary TargetNegative control compound for protein kinase C inhibition
Reversible: no
Product does not compete with ATP.
Target IC50: >100 µM as negative control compound for protein kinase C inhibition; 8 µM in blocking the activation of mitogen-stimulated protein kinase p70s6k/p85s6k in vivo
Cell permeable: yes
General description
A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100 µM). Blocks the activation of p70s6k/p85s6kin vivo (IC50 = 8 µM).
A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100 µM). Blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6kin vivo (IC50 8 µM).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Marmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6.Davis, P.D., et al. 1992. J. Med. Chem.35, 177.Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.
Packaging
1 mg in Plastic ampoule
400 µg in Plastic ampoule
Warning
Toxicity: Standard Handling (A)
This product has met the following criteria: