5059830001 Display Image

NS1738

Code: 5059830001 D2-231

Biochem/physiol Actions

Primary Targetα7 AChR

General description

A biarylurea derivative that acts as a selective positive allosteric modul...


read more

Your Price
£172.00 EACH
£206.40 inc. VAT

Biochem/physiol Actions

Primary Targetα7 AChR

General description

A biarylurea derivative that acts as a selective positive allosteric modulator selective for α7 nicotinic acetylcholine receptors (α7 nAChR) without substantial activity for α4β2, α3β3 and α1-containing receptors. Exhibits cognitive enhancing effects in vivo.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Freitas, K., et al., 2013. J. Pharmacol. Exp. Ther.344, 264.Timmermann, B., J. et al., 2007, Pharmacol. Exp. Ther.323, 294.Faghih, R., 2007. Recent Pat CNS Drug Discov.2, 99.

Packaging

10 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)

assay≥99% (HPLC)
colorbeige
formpowder
manufacturer/tradenameCalbiochem®
Quality Level100
solubilityDMSO: 100 mg/mL
storage conditionprotect from light, OK to freeze
storage temp.2-8°C
Cas Number501684-93-1
This product has met the following criteria: