LFM-A13, >=98% (HPLC), powder

Code: L6920-5MG D2-231

Biochem/physiol Actions

LFM-A13 is an inhibitor of the nonreceptor tyrosine kinase Bruton′s tyrosine kinase (Btk), a new molecular target for treatment of B-cell lympho...


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Your Price
£91.50 5MG
Discontinued
£109.80 inc. VAT

Biochem/physiol Actions

LFM-A13 is an inhibitor of the nonreceptor tyrosine kinase Bruton′s tyrosine kinase (Btk), a new molecular target for treatment of B-cell lymphoma and autoimmune disorders. LFMA13 inhibited recombinant BTK with an IC50 value of 2.5microM with 100-fold lower inhibitory activity against a number of other protein kinases including JAK1, JAK2, EGFR, IRK, IKK, and CDK1, 2 and 3, as well as several other related kinases

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
InChI keyUVSVTDVJQAJIFG-VURMDHGXSA-N
InChI1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-
Quality Level100
SMILES stringCC(O)=C(/C#N)C(=O)Nc1cc(Br)ccc1Br
solubilityDMSO: ≥19 mg/mL
storage temp.2-8°C
Cas Number244240-24-2
This product has met the following criteria to qualify for the following awards:



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