282200-100MG Display Image

Galangin, autophagy inducing flavonoid

Code: 282200-100MG D2-231

Application

Galangin has been used: as a test drug to test its ameliorative effect in a rodent model of cisplatin-induced nephrotoxicityto test its effect on the differentiat...


read more

Your Price
£443.00 100MG
£531.60 inc. VAT

Application

Galangin has been used: as a test drug to test its ameliorative effect in a rodent model of cisplatin-induced nephrotoxicityto test its effect on the differentiation of 3T3-L1 preadipocyte cells into adipocytesas an internal standard in nuclear magnetic resonance spectroscopy and mass spectroscopy

Biochem/physiol Actions

Galangin exhibits antioxidant, anti-apoptotic, anti-inflammatory and anti-obesity properties. In addition, it also possesses anti-genotoxic activity against environmental and dietary carcinogens. Galangin inhibits cancer growth by hindering cancer cell proliferation, induction of apoptosis and autophagy and inhibition of metastasis. Galangin also has an ability to inhibit CYP1A1 (Cytochrome P450, family 1, member A1) activity.

General description

Galangin is a flavonoid isolated from members of the Zingiberaceae family, which are mainly used for herbal medicines.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 282200.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

25, 100 mg in glass bottle

assay≥95% (HPLC)
coloryellow
formpowder
Gene Informationhuman ... ADORA2A(135), ADORA3(140), CYP1A2(1544)rat ... Adora1(29290), Adora2a(25369)
InChI keyVCCRNZQBSJXYJD-UHFFFAOYSA-N
InChI1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
mp214-215 °C (lit.)
Quality Level100
SMILES stringOc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccccc3
Code
Description
Unit Size
List Price
Qty
282200-25MG
Unit:25MG
List Price: £138.00
Source:List Price
ADD
Cas Number548-83-4
This product has met the following criteria: