Biochem/physiol Actions

Protein inhibitor of activated STAT (PIAS) family of proteins mediates the sumoylation of proteins by acting as SUMO E3 ligases. Some important proteins that are sumoylated by PIAS are p53, c-Jun and the androgen receptor.

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Immunogen

Synthetic peptide directed towards the C terminal region of human PIAS2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: LTSPLTASSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD