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BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct, may contain up to 1 mole equivalent of MTBE, 97%

Code: 718750-100MG D2-231

Application

Application Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst for: C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and seconda...


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Your Price
£92.20 100MG
£110.64 inc. VAT

Application

Application Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst for: C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines Amination reaction N-arylation of aminophenols

General description

BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. The formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. The resulting catalyst is very active, even at temperatures down to −40 °C, and can be used in a variety of cross-coupling protocols.

Packaging

100 mg in glass bottle

1, 5 g in glass bottle

assay97%
featuregeneration 1
formsolid
functional groupphosphine
InChI keyOWHWOTGYDWMPCA-UHFFFAOYSA-M
InChI1S/C35H53O2P.C8H10N.C5H12O.ClH.Pd/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28;9-7-6-8-4-2-1-3-5-8;1-5(2,3)6-4;;/h19-25,27-28H,9-18H2,1-8H3;1-4H,6-7,9H2;1-4H3;1H;/q;;;;+1/p-1
mp198-204 °C
Quality Level100
reaction suitabilityreaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Hiyama Coupling, reaction type: Heck Reaction, reaction type: Sonogashira Coupling, reaction type: Suzuki-Miyaura Coupling, core: palladium, reaction type: Negishi Coupling, reaction type: Stille Coupling, reagent type: catalystreaction type: Cross Couplings
SMILES stringCOC(C)(C)C.NCCc1ccccc1[Pd]Cl.COc2ccc(OC)c(c2P(C3CCCCC3)C4CCCCC4)-c5c(cc(cc5C(C)C)C(C)C)C(C)C
Code
Description
Unit Size
List Price
Qty
718750-5G
Unit:5G
List Price: £1,090.00
Source:List Price
ADD
Cas Number1148148-01-9
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