R9644-10MG Display Image

Ribavirin, antiviral

Code: R9644-10MG D2-231

Biochem/physiol Actions

Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavi...


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Your Price
£65.40 10MG

Biochem/physiol Actions

Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.

Antiviral agent. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases.

General description

Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.

Chemical structure: nucleoside

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R9644.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

50 mg in glass bottle

10 mg in poly bottle

antibiotic activity spectrumviruses
assay≥98% (TLC)
formpowder
Gene Informationhuman ... IMPDH1(3614), IMPDH2(3615)
InChI keyIWUCXVSUMQZMFG-AFCXAGJDSA-N
InChI1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
mode of actionDNA synthesis | interferes
Quality Level200
SMILES stringNC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
solubilitywater: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
R9644-50MG
Unit:50MG
List Price: £222.00
Source:List Price
ADD
Cas Number36791-04-5
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