457701-25ML Display Image

(S)-(-)-2-Methyl-CBS-oxazaborolidine solution, 1 M in toluene

Code: 457701-25ML D2-231

Application

CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis

(S)-(-)-2-Methyl-CBS-oxazaborolidine solution [1M in toluene] may be used as a cata...


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Your Price
£224.00 25ML
£268.80 inc. VAT

Application

CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis

(S)-(-)-2-Methyl-CBS-oxazaborolidine solution [1M in toluene] may be used as a catalyst in the multi-step synthesis of (-)-diospongin A.It may also be used in the preparation of:(1S)-2-azido-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol(R)-α-deuteriobenzyl alcohol(R)-2-(1-hydroxyethyl)benzo[b]thiophene

Excellent catalyst for asymmetric reductions.

The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols, and propargyl alcohols.

Catalyst employed in an enantioselective synthesis of (S)-2-amino-1-phenylethanol.

Other Notes

Precipitate may form in storage, but does not affect product quality. Gently heat product to 80-90 °C under an inert atmosphere to redissolve solids.

Packaging

5 mL in glass bottle

25 mL in Sure/Seal™

bp111 °C
concentration1 M in toluene
density0.929 g/mL at 25 °C
InChI keyVMKAFJQFKBASMU-KRWDZBQOSA-N
InChI1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m0/s1
Quality Level100
SMILES stringCB1OC([C@@H]2CCCN12)(c3ccccc3)c4ccccc4
storage temp.room temp
Code
Description
Unit Size
List Price
Qty
457701-5ML
Unit:5ML
List Price: £102.00
Source:List Price
ADD
Cas Number112022-81-8
Hazard Class3
Un Number1294
Pack Group2
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